Simon Sieber Research group
Simon Sieber Research Group
Research
Our research project focuses on developing innovative strategies to discover and characterize bioactive natural products from diverse sources. By integrating tools from chemical synthesis, metabolomics, and metagenomics, we can identify new compounds, link them to their biosynthetic origins, and explore their roles in natural systems.
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Selected Publications
Zhioua, S., Khan, I., Gonzalez, D., Junier, P.* & Sieber, S.*
Science of The Total Environment 993, 179750 (2025).
Genomic and chemical characterization of cytotoxic Ahp-cyclodepsipeptides from Phormidium using Thamnocephalus platyurus bioassay
Schäfer, R. J. B., Wilson, K., Biedermann, M., Moore, B. S.,* Sieber, S.* & Wennemers, H.*​
Chemistry - A European Journal 29, e202203277 (2023).
Identification of Isonitrile-Containing Natural Products in Complex Biological Matrices through Ligation with Chlorooximes
Chokshi, K., Kavanagh, K., Khan, I., Slaveykova, V. I. & Sieber, S.*
Environment International 189, 108813 (2024).
Surface displayed MerR increases mercury accumulation by green microalga Chlamydomonas reinhardtii
Müller, M. J., Dorst, A., Paulus, C., Khan, I. & Sieber, S.*​
Chemical Communications 58, 12560–12563 (2022).
Catch-enrich-release approach for amine-containing natural products
